Type 2 Diabetes Risk DNA Test
$349.00
Do you have a family history of type 2 diabetes? Do you have higher than normal blood sugar levels? Type 2 diabetes is generally associated with an unhealthy lifestyle and extra body weight, but genetic variations can also increase your risk, regardless of your lifestyle. Take this DNA test to determine if you have an increased risk of developing type 2 diabetes.
Description
Type 2 diabetes is a metabolic disorder that disrupts the body’s normal glucose and insulin balance. Glucose is a simple sugar that circulates in the blood and is the primary source of energy for the body’s cells, while insulin is a hormone produced by the beta cells of the pancreas and helps to keep glucose levels within a healthy range. Affected individuals have consistently high blood sugar, insulin resistance and a relative lack of insulin. Type 2 diabetes can contribute to life threatening disorders, including heart disease, stroke, kidney failure and poor blood flow.
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Test Details
Risk factors for type 2 diabetes:
- Obesity, leading to insulin resistance
- Fat accumulation, primarily in the abdomen
- Lack of physical exercise
- Ethnicity (Africans and American Indians have a higher risk)
- Prediabetes (elevated blood sugar)
- Gestational diabetes
- Polycystic ovarian syndrome
- Genetic variation
Genetic variations can affect our glucose and insulin levels, sensitivity to dietary fatty acids, and the way our body responds to insulin, resulting in increased risk of type 2 diabetes.
Detected Variants
ACC2 –Decreased insulin sensitivity.
ADCY5 – Impaired insulin secretion.
FABP2, FTO – Elevated uptake of saturated fats.
ADIPOQ, CRY2, FADS1, G6PC2, GLUT2, MTNR1B, PROX1, TCF7L2 – Elevated fasting glucose levels.
GCKR – Decreased fasting glucose levels.
GCK, HNF4A – Impaired pancreatic beta cell function.
GLIS3, IRS1, SLC30A8 –Dysregulated insulin production/signaling/storage.
SHBG – Elevated sex hormone binding globulin.
MADD – Disrupted proinsulin-to-insulin conversion.
SOD2 – Elevated reactive oxygen species.
HIF1A – Hypoxia resistance.
